What is granulomatosis with polyangiitis? (GPA, formerly Wegener’s)

Granulomatosis with polyangiitis (GPA) is a new term introduced to replace the name Wegener’s granulomatosis. As the term is being adopted, the terminology “granulomatosis with polyangiitis (GPA) has been proposed....

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What is the difference between systemic polyarteritis nodosa (PAN) and cutaneous PAN?

Polyarteritis nodosa (PAN) is a vasculitis affecting medium-sized blood vessels. In patients with “cutaneous polyarteritis nodosa”, the findings of the disease are localized to the skin (purpura or subcutaneous nodules), but also sometimes the peripheral nerve(s) of the same limb (causing weakness and/or numbness). Patients with systemic polyarteritis nodosa have…...

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Is athma a part of EGPA/Churg Strauss Syndrome?

Not exactly. Even though asthma is present in almost all patients with EGPA and corticosteroids represent the cornerstone treatment for both conditions, asthma it is not part of the vasculitis. In EGPA, asthma is more to be considered as an underlying predisposing condition, and it usually persists even after effective…...

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What is the difference between Takayasu and giant cell arteritis?

The key difference between Takayasu arteritis (TAK) and giant cell arteritis (GCA) is the age of the patients affected by the disorders. Takayasu arteritis affects younger patients, generally less than 40 years of age, while giant cell arteritis affects older patients, generally over 50 years of age. Both Takayasu arteritis…...

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How can I be in remission if my creatinine is still elevated?

Measuring the creatinine level in the blood provides an indicator of how well your kidneys are working. Higher creatinine levels mean worse kidney function. When you have a form of vasculitis affecting the kidneys, small filtering parts of your kidneys (glomeruli) are gradually being injured by your disease. The purpose…...

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