For people with autoimmune disorders/vasculitis, will IVIG have a detrimental effect similar to the disease?

In theory, vasculitis caused by immune complexes (cryoglobulinemia, polyarteritis nodosa, Henoch-Schoenlein purpura, and vasculitis associated with rheumatoid arthritis, lupus, or Sjogren’s syndrome) could get either better or worse with IVIG. Worsening of cryoglobulinemic vasculitis after IVIG (or rituximab, for the same reason) has been reported.

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