Disease Names

What is the difference between limited and severe granulomatosis with polyangiitis (GPA, formerly Wegener’s)?

Not all patients with granulomatosis with polyangiitis (GPA) have similar disease. The term “limited” GPA was introduced in 1966 and was originally defined as GPA that did not involve the kidneys. Unfortunately, this term has often been misinterpreted. “Limited” GPA is not equivalent to non-severe GPA as there are people…...

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How do I predict relapse in EGPA/Churg Strauss syndrome?

It can be hard to determine relapses in EGPA/Churg Strauss syndrome. A return of sinus symptoms and asthma is very common, but these but may not represent active vasculitis. These symptoms may require treatment with prednisone and are commonly the rate-limiting features in being able to reduce the prednisone dose…...

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