New VPPRN Study!

Help us develop a tool for determining the efficacy of treatments for patients with vasculitis!

A.R.C. | ANCA-Associated Response Criteria

This survey is part of a larger project sponsored by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) to develop response criteria for ANCA-associated vasculitis (granulomatosis with polyangiitis and microscopic polyangiitis) for use in clinical studies/trials.

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A.R.C. | ANCA-Associated Response Criteria

We are developing a research questionnaire as part of a larger project to develop response criteria for ANCA-associated vasculitis for use in clinical studies / trials.  We are looking for volunteers with granulomatosis with polyangiitis (GPA, formerly called Wegener’s) or microscopic polyangiitis (MPA) to complete this survey.

Response Criteria: How the Results of Clinical Trials are Measured

Response criteria:

A system for determining whether a patient has improved or not improved after starting a new treatment.

Response Criteria and Clinical Trials:

Currently, clinical trials in AAV use multiple endpoints to define active disease or remission. Treatment response beyond active disease and remission is not measured because no criteria exist for a range of disease states in AAV.

Since vasculitis is a complicated disease, such criteria may need to involve several different measurements of various features of the disease to decide if a patient is better, worse, or the same after treatment.

The Solution: Your Participation in A.R.C.

Developing response criteria that measures disease states beyond active disease and remission will improve the testing of treatments for vasculitis in the future.  We ask for your participation in this survey to help with the development of these new treatment response criteria.

About the Study

Aim of the Study

Develop data-driven criteria for a range of disease states and treatment response in AAV for use in clinical trials.

What is Involved

This is an online research questionnaire. There will be 4 rounds of this questionnaire. Your email address will be collected for the purpose of determining who has completed the survey; for example, we will re-contact you to complete all rounds of the survey. However, your name will not be linked to any specific responses.

Those who complete all 4 rounds will have the option to choose if they would like to be listed by name in the published study as a contributor.

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How to Participate

  1. CONSENT TO PARTICIPATE: Complete the consent form by clicking the “Join the Study” button below. You will be taken to the consent form for this study.
  2. COMPLETE THE QUESTIONNAIRE: Once you have consented to participate, you will be taken to the online questionnaire. It will take you approximately 15- 20 minutes to complete.
  3. KEEP COMING BACK: You will be asked to complete 3 additional questionnaires. You will be sent hyperlinks to the subsequent rounds via email.

The VPPRN study team is here to support you and make participation in vasculitis research easy. If you have any questions or concerns feel free to contact any of the individuals below.

Kaitlin Quinn, ACR Research Fellow and lead investigator for this Delphi exercise

[email protected]

Kalen Young, Director of Research Affairs VPPRN

[email protected]