Buerger’s Disease is vasculitis causing insufficient blood flow to the hands and feet, producing numbness, tingling and ultimately skin and gangrene. The classic Buerger’s patient is a male, between the ages of 20 and 40, although there is a higher percentage of women and people over the age of 50 being diagnosed. Buerger’s disease is most common in the Orient, Southeast Asia, India and the Middle East, but appears to be rare among African–Americans.
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ClinicalTrials.gov offers up-to-date information for locating federally and privately supported clinical trials for a wide range of diseases and conditions.
A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments.
Observational trials address health issues in large groups of people or populations in natural settings.
ClinicalTrials.gov currently contains 76,565 trials sponsored by the National Institutes of Health, other federal agencies, and private industry. Studies listed in the database are conducted in all 50 States and in 169 countries ClinicalTrials.gov receives over 40 million page views per month 50,000 visitors daily.
The U.S. National Institutes of Health (NIH), through its National Library of Medicine (NLM), has developed this site in collaboration with the Food and Drug Administration (FDA), as a result of the FDA Modernization Act, which was passed into law in November 1997.
(March 2002).